IV Chelation Therapy

Chelation therapy is a medical procedure that uses chelating agents—substances that bind to heavy metals like lead, mercury, aluminum, cadmium, nichel, gadolinium and arsenic—to remove them from the bloodstream. These agents, commonly administered intravenously or orally, capture toxic metals and facilitate their excretion via the kidneys or gastrointestinal tract. Functional medicine often uses chelation therapy when tests show high metal toxicity levels, but it emphasizes that chelation should be part of a broader detox strategy, including dietary changes, antioxidant support, and a focus on gut health to safely and effectively eliminate toxins from the body.

Chelation therapy introduces chelating agents that bind to toxic metals in the bloodstream. These agents, such as EDTA (ethylenediaminetetraacetic acid) or DMSA (dimercaptosuccinic acid), latch onto metals, creating a compound that the body can excrete through urine or stool. This therapy is usually performed under medical supervision, as chelation can impact essential minerals like calcium and magnesium. Functional practitioners often support chelation with nutritional interventions to replenish lost minerals and promote overall detoxification through diet and hydration.

Chelation therapy is FDA-approved for treating heavy metal poisoning. Functional medicine practitioners may still use chelation off-label for conditions like heart disease. Comprehensive patient assessment and monitoring are central to safe practice.

Chelation therapy is primarily used for heavy metal toxicity, but research and clinical practice have explored its potential benefits for cardiovascular diseases (TACT study by NIH), neurodegenerative disorders, and certain inflammatory conditions. Some believe that by removing toxic metals that contribute to oxidative stress, chelation may benefit conditions like heart disease or diabetes, though the evidence is still evolving. Functional medicine views chelation as part of a holistic approach, aiming to reduce environmental and dietary toxin exposures alongside detox therapy.

Chelation therapy has been used since the 1940s, initially for treating lead poisoning and later for other heavy metal toxicities. In recent decades, it has gained interest in functional and alternative medicine communities for broader applications, including cardiovascular health. While the approach has evolved, functional medicine continues to refine it by combining chelation with individualized protocols that enhance the body’s natural detox processes.

Chelation therapy primarily targets heavy metals such as lead, mercury, aluminum, gadolinium, arsenic, and cadmium, which can accumulate in the body over time and contribute to a range of chronic health issues. Each metal can impact different body systems; for example, lead affects neurological and kidney health, while mercury disrupts nervous and immune function. Functional medicine addresses these toxicities through individualized treatment plans, using chelating agents that best target specific metals and complementing them with supportive nutrition and lifestyle practices to minimize reabsorption and toxicity.

Individuals with documented heavy metal toxicity or exposure, particularly those experiencing symptoms such as fatigue, cognitive impairment, skin conditions, and immune dysfunction, may benefit from chelation therapy. Functional medicine practitioners emphasize the importance of testing for heavy metals before considering chelation, as it’s not a blanket solution for all health issues. People in high-exposure occupations or environments, or those with certain genetic susceptibilities to metal retention, may particularly benefit from carefully monitored chelation combined with lifestyle adjustments to reduce ongoing exposure and enhance detoxification.

Chelation therapy is generally safe when administered by a qualified practitioner but can have risks, mainly if administered improperly or without adequate mineral support. Chelating agents bind to toxic metals and essential minerals, potentially leading to deficiencies if not managed carefully. Functional medicine prioritize testing and monitoring throughout treatment, ensuring mineral balance, and providing dietary and supplemental support to reduce side effects and promote the safe elimination of heavy metals.

Common symptoms of detoxification as a result of chelation therapy include nausea, fatigue, headaches, and body ache, typically occurring as metals mobilize in the body. Functional medicine practitioners often preemptively address these potential side effects by advising on hydration, mineral supplementation, and gradual dosing protocols. In more severe cases, chelation can lead to mineral imbalances and kidney stress, so practitioners closely monitor these parameters to minimize adverse effects, adjusting therapy as needed based on individual tolerance and response.

Yes, chelation therapy effectively binds to heavy metals, aiding their removal from the body. Chelating agents latch onto metal ions, creating a compound that can be excreted. Functional medicine practitioners enhance this process by addressing overall detoxification, including liver and kidney support, hydration, and dietary strategies to support the body’s natural cleansing pathways.

Chelation therapy is most commonly used for lead, mercury, aluminum, cadmium, gadolinium and arsenic toxicity but is also explored for conditions like cardiovascular disease, Alzheimer’s, and diabetes. Functional medicine practitioners use chelation carefully in chronic illness cases where toxic metals are suspected to contribute to inflammation or oxidative stress. Treatment is always individualized, with an emphasis on lab testing to confirm toxicity before starting therapy.

Chelation therapy, particularly with EDTA, has shown some promise for improving heart health by removing calcium deposits in arteries and reducing oxidative stress. While not a first-line treatment, functional medicine may consider chelation as part of a broader strategy that includes diet, lifestyle, and stress management for those with cardiovascular concerns, especially where heavy metal exposure is a factor. (TACT study by NIH)

Chelation therapy has been explored in autism spectrum disorder, though it remains controversial. Some functional practitioners may consider it in cases with documented heavy metal toxicity; however, it is not a primary treatment for autism. Supportive therapies such as diet adjustments and gut health optimization are often emphasized first, with chelation used only in carefully monitored settings when toxicity is verified.

Yes, chelation therapy is a standard treatment for lead poisoning. EDTA and DMSA are commonly used chelating agents that are binding to lead and promote its excretion. Functional medicine practitioners prioritize careful monitoring and supportive nutrition to counterbalance potential side effects, ensuring the therapy is as safe and effective as possible for those with documented lead exposure.

Chelation therapy can be effective for mercury poisoning, often using agents like DMSA or DMPS. Functional medicine approaches prioritize slow, controlled chelation to minimize the risk of redistributing mercury within the body and emphasize detox support with hydration, antioxidants, and gut health interventions to remove mercury safely.

While research is ongoing, some believe chelation therapy might benefit Alzheimer’s by reducing metal-induced oxidative stress. Heavy metals are neurotoxins and can contribute to poor memory. Dr. Dale Bredesen emphasizes the importance of clearing the body of toxins and having a wholesome diet. Functional medicine practitioners are cautious, considering chelation only where heavy metal toxicity is evident and using it alongside other therapies that address brain health, such as anti-inflammatory diets, exercise, and cognitive support.

Chelation therapy may support circulation by reducing calcification in arteries and improving blood flow, particularly in peripheral arterial disease. Functional medicine considers it part of a broader circulatory health strategy, emphasizing anti-inflammatory nutrition, physical activity, and stress management to enhance cardiovascular benefits holistically.

Chelation therapy may offer benefits for diabetic complications by reducing inflammation and heavy metal burdens that can impact insulin function. Functional medicine practitioners, however, often address blood sugar management through diet, exercise, and stress reduction first, reserving chelation for cases with clear evidence of metal toxicity contributing to metabolic issues.

Chelation therapy is commonly administered intravenously, although oral forms such as DMSA are also very effective. Functional medicine practitioners choose the method based on the patient’s toxicity level and health status, ensuring that all supportive measures are in place to optimize safety and efficacy. Intravenous administration offers faster results but may require clinical supervision.

The number of sessions varies widely, typically ranging from 5 to 30 or more, depending on toxicity levels and treatment goals. Functional medicine practitioners closely monitor progress with regular testing, adjusting session frequency based on response and ensuring that any mineral imbalances or side effects are addressed along the way for a safe treatment course.

During a chelation therapy session, you’ll receive a chelating agent either intravenously or orally, depending on your treatment plan. If IV, you’ll be seated comfortably while the chelation solution is administered, typically lasting 1–2 hours. Functional medicine practitioners monitor blood pressure, hydration, and comfort throughout the session, ensuring your safety and comfort. Many patients report mild fatigue afterward, so rest and hydration are encouraged. Testing is often conducted periodically to assess progress and make any necessary adjustments.

Chelation therapy isn’t painful, though you may feel a slight pinch during IV needle insertion. Once underway, most patients feel comfortable and experience no pain. Functional medicine practitioners prioritize creating a relaxing environment and minimizing discomfort; some clinics offer supportive therapies like hydration or nutrient infusions to enhance comfort. Post-session, some may feel mild fatigue or slight nausea, which usually resolves with rest and hydration.

Each session typically lasts 1–2 hours, depending on the dosage and the patient’s needs. Functional medicine practitioners carefully monitor the duration and adjust based on the individual’s health, toxicity levels, and response. The goal is a practical yet gentle detox, minimizing side effects and allowing the body to safely process and excrete bound metals.

Before starting chelation therapy, patients often undergo lab tests to assess heavy metal levels, kidney function, and mineral status. Functional medicine practitioners recommend staying well-hydrated and maintaining a nutrient-dense diet to support detox pathways. Some may suggest baseline supplements to bolster mineral levels, as chelation can reduce essential minerals. Preparing the body with adequate hydration and nutrition ensures a smoother, safer experience with fewer side effects.

After a chelation session, it’s essential to hydrate well, as this helps flush out metals. Functional medicine practitioners often recommend resting, as some people feel fatigued afterward. Eating a balanced meal with sufficient protein and minerals may also help replenish essential nutrients that chelation can impact. Regular post-session blood tests are sometimes conducted to monitor metal levels and ensure a safe detox process.

While some oral chelating agents can be taken at home, intravenous chelation therapy should be done in a medical setting under professional supervision. Functional medicine emphasizes the importance of medical oversight for safety, as chelation can affect kidney function and mineral levels. Home treatments may be considered for mild cases but require careful guidance and follow-up testing to ensure efficacy and minimize risks.

Side effects can include mild nausea, fatigue, and temporary mineral depletion. Rarely, more severe issues like kidney strain or low blood pressure can occur. Functional medicine practitioners minimize risks by carefully dosing treatments, regularly monitoring kidney and mineral status, and recommending supportive therapies like mineral supplementation and hydration to counteract any nutrient losses or dehydration.

In rare cases, chelation therapy can put a strain on the kidneys, especially at high doses or with pre-existing kidney issues. Functional medicine practitioners use lower, personalized doses and regular testing to monitor kidney function, ensuring treatment is as safe as possible. Hydration and supportive nutrients are often encouraged to protect the kidneys and enhance detoxification.

Chelation therapy may pose risks for heart patients, particularly those with unstable cardiovascular conditions, as it can cause fluctuations in blood pressure and electrolyte levels. Functional medicine practitioners evaluate heart health carefully before starting therapy and adjust dosing accordingly. Some studies suggest chelation benefits circulation and vascular health, but it must be done under strict supervision to avoid potential complications.

Most patients experience no adverse long-term effects when chelation therapy is done under medical supervision. However, ongoing monitoring is crucial as chelation can deplete essential minerals over time. Functional medicine practitioners often supplement key minerals and nutrients during and after therapy, ensuring patients remain balanced and protected from nutrient deficiencies or other lasting impacts.

Chelation therapy may not be suitable for people with severe kidney disease, certain heart conditions, or specific mineral deficiencies. Pregnant women and individuals with underlying health issues should consult their healthcare providers. Functional medicine practitioners evaluate health history, lab tests, and overall resilience to ensure that chelation is safe and beneficial, tailoring the approach to each individual’s health profile.

Yes, chelation therapy can bind essential minerals like calcium, magnesium, and zinc, leading to nutrient deficiencies if not monitored. Functional medicine practitioners emphasize mineral repletion throughout treatment, often recommending supplements and nutrient-rich diets to maintain balance and prevent deficiencies, ensuring that the benefits of chelation outweigh any potential nutritional risks.

Research on chelation therapy is mixed, with solid evidence supporting its use in heavy metal poisoning but more limited data for cardiovascular and other chronic conditions. Functional medicine practitioners often consider it a complementary therapy, recognizing its potential to reduce metal toxicity and oxidative stress. They rely on patient-specific assessments, clinical experience, and ongoing studies to guide its use.

Experts are divided on chelation therapy; while toxicologists support its role in heavy metal detox, others view its broader applications with caution. Functional medicine experts see potential, especially for patients with documented toxicity, as part of a holistic detox approach. The therapy’s effectiveness may depend on individual health profiles, so thorough assessment and monitoring are central to its responsible use.

Chelation therapy has been studied in numerous clinical trials, notably the TACT (Trial to Assess Chelation Therapy) for heart disease. Results suggest potential benefits for cardiovascular health, particularly in diabetes patients, but more research is needed. Functional medicine practitioners cautiously incorporate such findings, emphasizing individualized treatment, holistic support, and chelation for optimized outcomes.

Absolutely. You can check our testimonials. Many patients report improvements in energy, mental clarity, acne and eczema clearance, reduction in joint and body ache, and reduced generalized symptoms after chelation therapy, especially when heavy metal toxicity was a factor. Functional medicine clinics often share anecdotal success stories, underscoring the importance of a personalized, integrative approach. However, viewing these cases as part of a broader context that includes lifestyle and health factors contributing to overall well-being is vital.

Depending on the chelating agent and clinic, chelation therapy costs range per session. Functional medicine practitioners work with patients to determine the frequency and total number of sessions needed. While costs can add up, many patients view chelation as a valuable investment in reducing toxic load and improving health. Some clinics offer financial plans or bundle packages to make it more accessible.

You can find accredited practitioners on the American College for Advancement of Medicine website. Qualified practitioners can be found in functional medicine clinics, environmental medicine centers, or integrative health practices. Verifying their credentials, training, and experience with chelation therapy is essential. Functional medicine associations often provide directories.

Alternatives include diet-based detoxification, saunas, and nutritional support for natural detox pathways. Functional medicine practitioners often recommend these approaches for mild toxicity cases or in conjunction with chelation. Regular testing, lifestyle adjustments, and targeted supplements are part of an integrative strategy to reduce toxic load and improve health without reliance solely on chelation.

Reputable chelation therapists have credentials in functional or integrative medicine, with specialized training in environmental toxicity and detox therapies. Checking for affiliations with recognized medical boards and reviewing patient testimonials can help verify expertise. Functional medicine practitioners emphasize individualized care, comprehensive testing, and patient education as markers of a reputable therapist.
Dr. Lalezar is accredited for Chelation Therapy by the American College for Advancement of Medicine.