Adrenals are walnut shaped glands sitting right on top of our kidneys and they are the work horses of the endocrine system.  They produce Cortisol, Epinephrine, Norepinephrine, DHEA, and Testosterone. Prolonged emotional stress, poor sleep quality, blood sugar fluctuations, and inflammation are the cause of adrenal fatigue. Adrenal fatigue is manifested in three stages.

The first stage of adrenal fatigue is very gradual and insidious.   It’s caused by prolonged stimulus to the adrenal glands, an increase in cortisol output, and a decrease in DHEA level.  In this stage, Estrogen, Progesterone, and Testosterone levels are also altered, which in turn effect the immune system and the metabolic rate.

In Stage two of adrenal fatigue, cortisol level continues to decline throughout the day but goes up in the evening.  DHEA level declines as well.   In this phase of adrenal fatigue, the patient may develop depression, sweet cravings, decreased sex drive, insomnia, poor memory, anxiety, premenstrual syndrome, weakened immune response, recurrent infections, unexplained nervousness or irritability, inability to lose or gain weight, and joint or muscle pain.

The third stage of adrenal fatigue occurs when adrenals fail to meet the demands and are no longer able to produce cortisol.  In this crash phase evening cortisol level is also very low.  Severe other hormonal imbalances occur in this stage as well.  In this phase chronic fatigue occurs and the individual is unable to perform routine daily activities or work related duties.

This diagram illustrates the common pattern of the hormone cortisol through the stages of adrenal exhaustion. The total cortisol sum as measured in nano molars (nM) is shown to rise then fall as the stages of exhaustion progress from left to right.

Adrenal Fatigue

Adrenal Function Evaluation
Cortisol level is evaluated through collections of 4 saliva samples: upon awakening, lunch time, mid afternoon, and before bedtime.

Neurotransmitters such as Serotonin, Epinephrine, Norepinephrine, Dopa, GABA, Glutamine are evaluated through a urine test.

Treatment
The fastest and most effective way to rejuvenate the adrenal glands is through IV vitamin therapy.  For stage 1 of adrenal fatigue Dr. Lalezar would recommend the Myers’ Cocktail which consists of Magnesium and B Vitamins to calm the adrenals, reduce production of cortisol and alleviate stress.

She would recommend the Vitality drip which consists of 15-30 grams of vitamin C, minerals, B vitamins, Zinc, Chromium, Magnesium, and Calcium for stages 2 and 3 of adrenal fatigue.  In addition, she may also recommend Glutathione IV which consists of three amino acids and is a very powerful antioxidant.

Adrenal support supplements made of the best quality nutrients are also recommended.  As a last resort Dr. Lalezar may prescribe physiologic doses of Hydrocortisone to help heal the adrenal glands.  Please refer to Dr. William Jeffries’ book “Safe Uses of Cortisol”.

How do I find out more about Adrenal Fatigue?
Call the Health & Vitality Center at 310-477-1166 or click here to schedule an appointment. We are one of the leading centers for natural medicine in Los Angeles. Holistic doctor Shiva Lalezar not only treats adrenal fatigue, she employs methods that prevent it from negatively impacting your everyday life. Our practice uses an integrative approach, combining the best conventional therapies with the latest techniques and treatments in functional medicine for optimal results.

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